1. Situs Judi Slot Terlengkap
  2. Situs Slot Online Terbaik Dan Terpercaya No 1
  3. Slot Pragmatic Play
  4. Situs Slot Online Terpercaya
  5. Kumpulan Situs Judi Slot Terpercaya
  6. Game Slot Online
  7. Judi Slot Online Jackpot Terbesar
  8. Situs Judi Slot Online Terpercaya 2021
  9. Slot Joker123
  10. Agen Slot Online Resmi
  11. Slot Deposit Pulsa
  12. Daftar Situs Judi Slot Terbaik Dan Terpercaya No 1
  13. AloJudi Slot
  14. Situs Slot
  15. Judi Slot Online Jackpot Terbesar Gampang Menang
  16. Mesin slot gacor 88
  17. Mesin slot
  18. Link Slot Online
  19. Slot Via Dana
  20. Daftar Situs Bo Slot Online Gacor Terbaik 2022
  1. Slot Online Terpercaya
  2. Judi Slot Online Jackpot Terbesar
  3. Daftar Situs Judi Slot Online Terpercaya
  4. Judi Slot Terpercaya
  5. Kumpulan Situs Judi QQ Online Terpercaya
  6. Situs Slot Deposit Pulsa dan Slot Online Terbaik
  7. Slot Hacker
  8. Situs Slot Online Terbaik
  9. Slot Gacor Gampang Menang
  10. Slot Online
  11. Situs Slot Online Terbaik 2022
  12. Slot RTP Pragmatic
  13. Situs Slot Gacor 2022

Abstract

SIMPLE UV SPECTROPHOTOMETRIC ASSAY OF CIPROFLOXACIN

Author(s): Safila Naveed* and Nimra Waheed

Objective:Ciprofloxacin is an established broad-spectrum fluoroquinolone antibiotic displaying activity against both Gram-positive and Gram-negative bacteria pathogens. It acts principally by inhibiting DNA-gyrase and topoisomerase IV present in bacterialcells which are responsible for reproduction of DNA of bacteria. A rapid, simple, accurate, and economical least time consuming spectrophotometric method has been developed for the assay of Ciprofloxacin and then compare it with the  assay of different brands available in Karachi, Pakistan.  A sample of drug was dissolved in water to produce a stock solution containing ciprofloxacin.Methods:Samples of ground tablets of different brand  were  taken  and  their  diluted  solutions  of  100ppm,  50ppm  ,  25ppm,12.5ppmand  6.25ppm  were  prepared  with  the  same  solvent.  The  assay  was  determined  by measuring the absorbance of stock solution against the solvent blank and comparing with the absorbance of available brands ofciprofloxacin at the wavelength of 278 nm by spectophotometer. Results:The percent assay is calculated and the correlation coefficient for different brands was found to be 0.9998 for (A), 0.9992 for (B), 0.9996 for (C) and CYCIN (D), 0.9989 for (E) and 0.9986 for (F) which are within the limit.  Conclusion:Thus we can conclude that the method can be applied for the routine QC quantitative analysis of ciprofloxacin in active and tablet formulation.

Get the App