SINDHU S*, S MANORAMA &ALFAMOL PM
PiperlongumL. (Thippali) is a native of the Indo-Malaya region, belongs to family Piperaceae. It has been used as a therapeuticagent in the treatment of various pathological conditions. P.longumwas reported to contain alkaloids, phenols, tannins, flavanoids, steroids, lignin & saponins in it. The objective of study isto evaluate the antimicrobial activity with their preliminary phytochemical study. The petroleum ether, acetone and ethanol extracts of all the parts (Leaf, fruit, stem and root) were tested for antimicrobial activity against certain bacterial strains of E.coli, Steptococcus faecalis, Steptococcus pyogensand SalmonellaparatyphiA. by in vitro disc diffusion method and the results are recorded as the zone of inhibition.