Khaled N. Rashed1*, Michele Garcia da Cruz2, Julia Medeiros Souza2, Lizandra Guidi Magalhaes2, Wilson R. Cunha
Objective: This present research work was carried out to evaluate shitosomicidal and leishmanicidal activities of Lagerstroemia tomentosastems methanol 80% extract and also the investigate the phytochemical content of the plant extract. Methods: Methanol 80% extract of Lagerstroemia tomentosastems was tested using Schistosoma mansoni and Leishmania amazonensis assays. Results: The results showed that methanol 80% extract of Lagerstroemia tomentosahas a little or no activity against S. mansoni or L. amazonensis, respectively. Against S. mansoni, the extract showed no the lethal effect, but it was observed a reduction in the motor activity at highest concentrations. On the other hand, against L. amazonensis, the methanol 80%extract caused lysis of only 25.0±6 of parasits at concentration 400μg/mL. Phytochemical analysis of methanol 80% extract of Lagerstroemia tomentosahas shown the presence of phytochemicals as triterpenes, flavonoids, tannins and carbohydrates. Conclusion: This study highlights the shitosomicidal and leishmanicidal activities of Lagerstroemia tomentosastems methanol 80% extract and also its chemical content.