Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315)

Author(s): MOHAMAD REZA HAVASIAN, PARNIAN TAJBAKHSH, JAFAR PANAHI

Objective:Staphylococci  aureus  and  Coagulase-negative  staphylococci  (CoNS)  are  a  major  source  of  infections  associated  with  indwelling  medical  devices.  Macrolide antimicrobial agents are widely used across the world to protect against bacterial infection. Methods:This  is  a  systematic  review  study  valuating  all  pubmed,  science  direct,  Scopus  and  Google  scholar  articles  about  the  Evaluation  of  macrolide  resistance  in Staphylococcus aureus between 2010 –2013 using analytical statistical analysis. Data were collected and the related information extracted and put in statistical package and analyzed. Results: According the result of this study prevalence of macrolide resistant in some of region was more than other region and it caused by different conditions. The most common genes in macrolide resistant was erm(A) but could not be found in regulatory region of the isolates. Conclusion: We should try to reduce the resistant to antimicrobial drug by set the healthy plane and reduce using of antimicrobial drug.