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Abstract

EVALUATION OF ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACTS OF MIMOSA PUDICA LEAVES

Author(s): M.SUNIL1, L.NAGAKRISHNA1*, SOUMENDRA NATH MAITY1,2, NAGABABU PYADALA2, PRUDHVI CHAND MALLEPADDI2, KUMAR SAI SAILESH,3RATHNAGIRIPOLAVARAPU

Objective: This study was carried out with an objective to investigate the antibacterial activity of ethanolic extracts of mimosa pudica. Methods: In the present study, the anti microbialactivity  of  ethanolic  extractsof Mimosa  pudica wasevaluated  against  medically  important  bacterial    strains,  two  Gram-positive—Staphylococcus  aureus and  Streptococcus pyogenes and  two Gram-negative—Escherichia coli and Pseudomonas aeruginosa. The antimicrobial activity was determined with the extract using agar disc diffusion method. The antibacterial activities of extracts (5, 25, 50, 100, 250 μgm/ml) of Mimosa pudica were tested against human pathogenic bacteria. Zone of inhibition of extracts  were  compared  with  the  standard  drug  ampicillin  for  antibacterial  activity. Results:The  results  showed  that  the Mimosa  pudica has  the  antibacterial  activity. Conclusion:  The  antimicrobial activity  of Mimosa pudica was due  to  the  presence  of  various  secondary  metabolites.  Hence,  these plants  can be  used  to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.

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