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Abstract

DIFFERENT SHADES OF NANOTHERAPEUTICS

Author(s): RENU KHANCHANDANI*, BHAVANA SRIVASTAVA, REENA BHARDWAJ, SANJAY GAUR, SANDEEP GAUR

Research and development of innovation drug delivery system are increasing at rapid pace throughout the world. The major factors that determine the treatment outcome in a patient  are  the  efficacy  and  safety  profile  of  drug  so  newtherapies  with  increased  efficacy  and  minimal  toxicity  are  of  utmost  need  for  better  public  health.  For  that  one, important  aspect  is  development  of  wide  spectrum  of  nanoscale  technologies  which  allow  innovative  therapeutic  approaches  and laid  the  foundation  of  Nanomedicine. Nanomedicine comprises of three main subsections Nanotechnology, nanobiotechnology and nanobiomimetics. The spirit of this combinational attribute allowsnanomedicine to crowned with the little of “revolutionary interdiscipline.” Thereare many innovative plateform of nanotherapeutics;mainly systems based on lipid or polymeric nano particles. Today many drug delivery system based on nanotechnology are in market like cancer, AIDS, fungal infection, viral infection, gene therapy even fordiagnostic purposes and orthopedic  biomaterial.  These  smart  multifunctional  nanoparticle  delivery  devices  can  be  value-added  for  optimized  therapeutic  activity  and  lead  to  development  of  safer, precise  and  less  intrusive  form  of  medical  practice i.e.personalizedmedicine.  Nanoparticles  are  also  associated  with  potential  pitfalls  or  undesirable  side  effect.  They  are hazardous for health and ecosystem. Approaches should be done to design safer nanotherapeutics by carring out toxicity study and by setting safety profile of nanoparticles

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