Harshavardhan Pathapati*1, T.E. Gopala Krishna Murthy2, B. Ramanaiah3, Davu Srinivas
Objectives:Diabetes is a metabolic disorder mainly impairs the body glucose utilization capacity due to this perforcely repressingthe immuno-dysfunction (decreases chemotaxis, phagocytosis and intracellular killing actions) and collagen synthesis which are essential in wound debridement management of diabetic patients. Delayed wound healing is considered as one of the most repulsivedisabling and costly complication of diabetes. People with diabetes have extenuated circulation, poor resistance to infectionand mitigate local nutrition, thus their wounds are meticulously susceptible to infection. Moreover diabetes agonizes the equilibrium exists between accumulation of extra-cellular matrix components and their re-modeling by matrix metallo-proteinases (meltrin), due to this extenuated proliferation action of fibroblasts and finally freezes the progress of wound healing frequency in hyper glycemics. However in diabetic persons the nervous system becomes numb and all feasible actions of neurons are skipped, that condition is called as diabetic neuropathy. In that situation patient body features elevated a glucose level which stiffens thearteries and lack of pain sensation in foot resulting in commencement of new wounds. Conclusion:Consider all problems associated with wound healing in diabetic persons, a proper wound healing management which includes controlling measures like optimized systemic and local factors as well as implement suitable wound dressing for necessary wound in diabeties patients.