COMPARITIVE STUDY OF DIFFERENT BRANDS OF ATENOLOLAVAILABLE IN KARACHI

SAFILA NAVEED; HUMA DILSHADAND SAMREEN AZIZ

Abstract

COMPARITIVE STUDY OF DIFFERENT BRANDS OF ATENOLOLAVAILABLE IN KARACHI

Author(s): SAFILA NAVEED*, HUMA DILSHADAND SAMREEN AZIZ

Atenolol is used in blood pressure therapy and available as different brands in the market which makes it difficult to select the brand. The aim of this study is to establish pharmaceutical equivalence among the differentbrands of atenolol tablets available in Karachi, Pakistan. Four different brands of atenolol tablets (100 mg) were included in the study. Quality control analysis using parameters: weight variation test, thickness, hardness test, friability and disintegration test were carried out specified USP and BP (United state and British Pharmacopoeia). Hardness value requirement was complied by all brands .Disintegration time for all brands was within 15 minutes complying the USP/BP recommendation. All brands showed more than 90 % drug release within 45 minutes. The present analysis suggest that all the brands of atenolol that are available meet the BP/USP specification for quality control analysis

tipobet vdcasino ven�sbet sahabet sekabet sahabet onwin matadorbet casibom casibom casibom casinoplus casibom casibom jojobet jojobet jojobet grandpashabet grandpashabet grandpashabet