Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315)

Author(s): ALMOTTESEMBELLAH ABDALRUHMAN GAIZ1,JAWAD KADHIM MSHALI2,AMEERA JASIM AL'ARAJI3

Objectives:Valuation  of  serum  calcium  in  the  patients  of  hematological  malignances,  and  correlation  between  serum  calcium  and  absolute  WBC  count  in  those  patients.Methods:Eighty eight patients of variable hematological malignancies referred to the national center of hematology treated with multiple drugs regarding the condition, each patient  assessed  with  full  name,  age,  gender,  disease  diagnosed  and  medications  received,blood  sample  withdrawn  and  handled  by  EDTA  tube  and  plain  tube  then processed in the laboratory to estimate complete blood count, serum calcium.results:Eighty eight patients with mean age is 43.14+15.73 (15-79 years). Male gendermildly more  than  female.  There  are  many  hematological  malignancy  cases  but  the  most  predominant  one  (68%  of  cases)  is  chronic  myeloid  leukemia  (CML).  There  is  positive correlation between serum calcium and absolute WBC count.Conclusion:There is positive correlation between serum calcium and absolute WBC count. Most of cases (53 cases) had received imatinib and present with a mean serum calcium value at 1.94 mmol/l which is less than normal range. In our study more than fifty cases ( more than 60%) present with decreased serum calcium.