Abstract

ASSESSMENT OF ANTIMICROBIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF Monodora myristica(EHURU) SEEDS

Author(s): UKAEGBU-OBI, K.M.1*, MERIBE, M.O.1AND ODO, C.E.

Objective:To assess the antimicrobial activity of Monodora myristicaseeds on four selected human pathogens,Escherichia coli, Staphylococcus aureus, Salmonella typhi, and Pseudomonas aeruginosa. Methods:Disc diffusion technique was used for in vitroantibacterial screening. Results:The most susceptible bacteriumwere E. coli(17mm) while  the  most  resistant  bacterium  was P.  aeruginosa.  The  minimum  inhibitory  concentration  result  showed  that  the  seed  extracts  of M.  myristicawas  bacteriostatic. M. myristicaextracts  when  compared  with  some  conventional  antibiotics  had  less  sensitivity  action  against  the  test  organisms. Conclusion:Our  findings  show  that  the  seed extracts of M. myristicapossess some antimicrobial activities which can be employed in the development of novel therapeutic agents against the test organisms

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