Abstract

ARE SMEDDs AND SNEDDs SAME? A GIMMICK OR PHARMACEUTICALLY RELEVANT

Author(s): Vivek P. Chavda

From the last two decades, the area of pharmaceutically research is highly being diversified for generating newer and better self emulsifying system; from micron to nano size. The applications are wide and generally oriented towards an increase in the bioavailability of drugs, solubilized—due to their submicron size and great (kinetical or thermodynamical) stability of the suspensions—into the oil droplet core. In most of the articles and in litratutres the micro and nanoemulsions are being described indiscriminately. Although this misconception appears to be common, these two systems are fundamentally different, based on very different physical and physicochemical concepts. Their differences result in very different stability behaviors, which can have significant consequences regarding their applications and administration as nano medicines. In this article the attempt is being made to solve this misconception which will be beneficial to the formulation scientists and students. Finally, an illustration is given; how to clear up this misconception using simple experiments

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