RAJ KUMAR TIWARI, AKANSHA SHARMA, RAVINDRA KUMAR PANDEY, SHIV SHANKAR SHUKLA
Objective: Diabetes associates not only rise in blood glucose level but also several diseases. One of the basic diseases is diabetic nephropathy. This is also called end stage diabetes. Method: The various factors which are responsible for the disease are elevated metabolism, hypertension, and blockage of various molecular pathways such as AGE, RAAS, PKC, Hexsomamine and polylol. When we considered for its treatment, is associated with various multiple risk factor approach. Along with allopathic medicine herbal medicine had provided a sensible and better approach for the treatment of various kidney diseases. Effective approaches must be applied for the prevention of development Hyperlipidemia, decrease GFR and sustaining the progression to later stages of nephropathy may be beneficial. Conclusion: This review mainly explains the pathophysiology and all the basic causes of diabetic nephropathy along with the potential herbs which may be useful for the treatment of disease.