Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315)

Author(s): P.MOUNIKA, SUSHMAA MUCHUKOTA, KISHORE.M.R, MOHIT KUMAR, MD ANBARUL RAIN

Context: The drug release assessment increasingly accepted by imaging technologies .They give proof for their in vivo release of controlled and sustained release dosage forms. The imaging technologies are X-rays, magnetic resonance imaging and ultra sound, gamma scintigraphy. These are the tools for the assessment of oral, pulmonary, and ophthalmic dosage forms. Objective: In this review mainly focus on gamma scintigraphy. This as a tool for the assessment of formulation deposition. Gamma scintigraphy is a non-invasive method with development of drug products and the assessment of pharmacodynamics effects in humans. From this method we can able to understand drug performance and critical parameters like gastrointestinal transit; gall bladder emptying; lung mucociliary clearance provides insights into the mode of action of drug candidates. Methods: In this review focus on the functional terms of gamma scintigraphy and their applications in pharmacy. Deposition control, temporal control, Barrier control.